Frank Edwards (March 20, 1909, Washington, Georgia, USA – March 22, 2002, Greenville, South Carolina, USA) was an American blues guitarist, harmonica player and singer. He was variously billed as Mr. Frank, Black Frank and Mr. Cleanhead. He recorded for three record labels in his career; Okeh Records in 1940, Regal Records in 1949, and Trix Records in the mid-1970s. Some more recent sessions were done for the Music Maker Relief Foundation. His most noted recordings were "Three Women Blues" and "Terraplane Blues".


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