Andre Williams (born Zephire Andre Williams in Bessemer, Alabama, on November 1, 1936) is an American R&B and punk blues musician who started his career in the 1950s at Fortune Records in Detroit. Some sources believe that Williams is the long-lost brother of Screamin' Jay Hawkins, a blues musician whose song "I Put A Spell On You" landed on the Rock and Roll Hall of Fame's 500 Songs that Shaped Rock and Roll charts.

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