Leguizamo was born in Bogotá, Colombia to Alberto and Luz Leguizamo.[1] His paternal grandfather was of Italian and Puerto Rican descent;[2] his maternal grandfather was Lebanese.[3] Leguizamo's father was once an aspiring film director and studied at Cinecittà but eventually dropped out due to lack of finances.[4] When Leguizamo was three years old, his family emigrated to the United States[5] and lived in various neighborhoods of Queens in New York City.

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