Serge Chaloff (November 24, 1923–July 16, 1957) was an American jazz baritone saxophonist, and the son of noted Boston piano teachers, Margaret Chaloff and Julius Chaloff. He is one of the few major jazz performers on his instrument, and the first major bebop performer, and was originally influenced by Charlie Parker. He first became well known as one of the "Four Brothers" reed section in Woody Herman's Second Herd.

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